Diffuse Axonal Injury
The
 brain consists of billions of nerve cells located in the gray matter 
which communicate with distant nerve cells through long nerve fibers 
called axons, composing the white matter. Severe sudden twisting or 
torquing of the brain, as occurs in a sudden acceleration/deceleration -
 whiplash -- accident, can stretch, twist, and damage these delicate 
axonal fibers. Under the microscope the axonal damage is called Diffuse 
Axonal Injury (DAI). Although diffuse axonal injury generally results 
from a severe whiplash injury that renders a patient comatose, recent 
studies have shown that diffuse axonal injury can also occur - but to a 
lesser degree -- when there has been only brief loss of consciousness 
(LOC). Because Diffuse Axonal Injury causes microscopic damage, it 
cannot be visualized on CT or MRI scans.
A
 second method of how the brain can be injured in high speed velocity 
change scenarios (a fall from a great height, high speed car accident) 
is called “Isotropic Stress.” Whereas diffuse axonal injury involves the
 deforming or stretching of the brain tissue, resulting in tearing, 
isotropic stress causes damage through a “pulse” or “pressure wave” that
 moves through the brain at extraordinarily high speeds. The damage is 
caused by a sudden change in the density of the inside of an individual 
brain cell. The instant compression causes damage to the internal 
structures of the brain cells.
Many
 of these same types of injuries have been discovered and treated in 
veterans returning from the Iraq war. They have often been exposed to 
the proximity blast of explosive charges. The pressure or pulse from the
 explosion moves through their body and as it move through the brain it 
causes damage to the cells. Although many of these soldiers look “fine” 
and have no bleeding, they can and will suffer serious brain injury as a
 result.
Because
 of the large number of veterans injured in this way, lots of research 
is being done on this type of brain injury at the present time and there
 should be studies available for an update on this new insight into TBI 
in mid-2008.
Braininjury.com
 
 
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